Silk, Mitchell Ramesh; Price, Jason R.; Mohanty, Biswaranjan; Leiros, Hanna-Kirsti Schrøder; Lund, Bjarte Aarmo; Thompson, Phillip E.; Chalmers, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-20)
Our understanding of the factors affecting the stability of cyclic d / l peptide (CP) nanotubes remains underdeveloped. In this work, we investigate the impact of side chain alignment, hydrophobicity and charge on CP nanotube stability through X-ray crystallography, NMR spectroscopy and molecular dynamics (MD) simulations. We characterise the distinct CP-CP alignments that can form and identify ...